TBK1 基因参与多种细胞过程，如先天免疫、自噬和细胞程序性死亡。但在 ALS 发病机制中，TBK1 基因功能缺失影响的众多途径尚未完全明确，且缺乏合适的体内模型来深入探究。为了填补这些空白，来自法国 Imagine Institute 等机构的研究人员开展了一项极具意义的研究，相关成果发表在《Cell Death Discovery》上。

Startup Cognixion, which has developed a noninvasive brain-computer interface, has begun a clinical trial for patients with ...

2025年2月24日， 北京大学第三医院（以下简称“北医三院”）神经内科樊东升教授团队在权威期刊、JAMA杂志子刊JAMA Network Open上发表了题为“Tetramethylpyrazine Nitrone in Amyotrophic ...

在研究结论与讨论部分，此次研究表明，ALS 患者在疾病早期就存在视觉空间能力的损伤，涉及感知和表征能力。这一发现提示，仅依赖标准筛查工具评估基本视觉感知技能，可能会低估 ALS 患者视觉空间缺陷的程度，忽略与后皮质萎缩相关的视觉空间缺陷，而后皮质萎缩与 ALS ...

Positron emission tomography (PET) is a nuclear imaging technique used to diagnose conditions such as cancer. An innovative ...

AKGsOVIHAMS, a leading healthcare institution, has marked progress in treating ALS using integrative medicine. Known for combining conventional and alternative therapies, the institute has shown ...

A new study compares three types of blood biomarkers: neurofilament light chain proteins, glial acidic proteins and phosphorylated tau 181.

Among participants who met the core RESTORE-ALS Trial criteria (e.g., baseline serum NfL > 33 pg/mL, TRICALS risk score range between –6.5 and –2.5, baseline slow vital capacity > 60%, and symptom ...

Denali Therapeutics’ amyotrophic lateral sclerosis (ALS) drug has racked up another clinical miss this year, leaving the ...

Recent studies have highlighted a link between amyotrophic lateral sclerosis (ALS) and gut microbiota. This prospective study aimed to evaluate the effects of electroacupuncture combined with Chinese ...

"Receiving orphan drug designation from the FDA is a significant milestone for DiagnaMed and validates the promise of molecular hydrogen as a potential treatment for ALS. We are excited to partner ...

Fully human intranasal foralumab shows promise in treating Secondary Progressive Multiple Sclerosis, Alzheimer's, and ALS.