The last mainline entry was Mega Man 11. That showed up back in 2018. That also featured a 2.5D type of presentation and traditional types of level design. While no new ports of it appeared since, ...

Build your class, break the cycle. A 2.5D turn-based roguelike where the skills you gain become your class. A 2.5D Turn-Based Roguelike Skill Builder Eternity Breaker is a Turn-based Roguelike game ...