本文开发了一种稳定性指示超高效液相色谱-质谱联用（UHPLC–MS）方法，系统研究了依来曲普坦氢溴酸盐（ELE）在ICH推荐的强制降解条件下的行为。研究首次分离并利用高分辨质谱（HRMS）和二维核磁共振（2D-NMR）完整表征了其在酸性和氧化条件下产生的四种降解 ...

WEST LAFAYETTE, Ind. — The same technology behind MRI images of injury or disease also powers nuclear magnetic resonance (NMR) spectroscopy, which is used to analyze biological molecules for research ...

An initial step of most NMR studies is identifying peaks in the obtained spectrum. Producing a peak list is especially crucial if the spectrum is automatically prepared. Peak picking is still ...

Purdue University physicist Tongcang Li performs optically detected magnetic resonance spectroscopy in his lab. Li and his team at Purdue are working on materials that would improve the resolution of ...

Have your data emailed to you when the acquisition is completed! Use this instrument for 1H, 19F, 19F{1H}, 13C, 11B, 31P, 29Si, 195Pt, or practically any "X" nucleus with automatic probe-tuning. This ...

NMR (Nuclear Magnetic Resonance) spectroscopy is a powerful analytical technique that provides detailed information about the structure, dynamics, and chemical environment of molecules at the atomic ...

The emergence of peptide therapeutics marks a transformative shift in the types of products being developed and manufactured in the pharmaceutical industry. Peptides, defined by the FDA as biopolymers ...