Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that ...

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by the aggregation of alpha-synuclein in the brain. Now, scientists have developed a radioligand that facilitates the ...

In the healthy brain, α-synuclein leads a dynamic life near the synapse, where it frequently shifts its conformation as well as its association with membrane vesicles. Disruption of this active ...

A new study has developed an assay that can identify incorrectly folded α-synuclein, a biomarker of synucleinopathies, in patient serum. Synucleinopathies are neurodegenerative diseases, such as ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, forms an abnormal connection with an enzyme called ClpP. This enzyme normally ...

Much of the research into α-synuclein, the major component of Lewy bodies in Parkinson’s and other neurodegenerative diseases, focuses on its role in synaptic vesicles and membranes. But could other ...

In a recent study published in the Proceedings of the National Academy of Sciences, researchers assessed the capability of two small molecules of disintegrating alpha-synuclein fibrils. Parkinson's ...

SynuSight Biotech has licensed 18F-FD4 to XingImaging and to ABLi Therapeutics to evaluate alpha-synuclein clearance from the brain in response to risvodetinib treatment ...

Active immunotherapy with ACI-7104.056 induces high anti-a-synuclein antibody levels on average 16-fold higher than placebo after 3 immunizations 100% of patients receiving ACI-7104.056 responded ...

SHANGHAI and ATLANTA and NEW HAVEN, Conn., Jan. 05, 2026 (GLOBE NEWSWIRE) -- SynuSight Biotech (“SynuSight”), a biotechnology company dedicated to the development of diagnostic solutions for ...