An investigation by researchers from Case Western Reserve University School of Medicine in the US has filled in a missing link between the toxic build-up of proteins in the neurodegenerative condition ...

Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that ...

The study, conducted in mice and published in the Nature journal, identifies a key role of gut macrophages -- a specialised immune cell that kills pathogens -- in the transfer of toxic proteins from ...

After three years of study, the researchers found that alpha-synuclein, a protein closely linked to Parkinson’s disease, ...

Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by the aggregation of alpha-synuclein in the brain. Now, scientists have developed a radioligand that facilitates the ...

New research reveals how Parkinson's spreads from the gut to the brain, with the help of immune cells—offering a new ...

In the healthy brain, α-synuclein leads a dynamic life near the synapse, where it frequently shifts its conformation as well as its association with membrane vesicles. Disruption of this active ...

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads ...

If the eyes are windows into the soul, Axim Biotechnologies believes that tears can provide a peek into the inner workings of the brain—and potentially carry with them the signs of Parkinson’s disease ...

Much of the research into α-synuclein, the major component of Lewy bodies in Parkinson’s and other neurodegenerative diseases, focuses on its role in synaptic vesicles and membranes. But could other ...