Biomarker changes that occur in the period between normal cognition and the diagnosis of sporadic Alzheimer’s disease have not been extensively investigated in longitudinal studies. We conducted a ...

A total of 1,007 cases and 1,007 controls were included. The most frequent cancers were BC (n = 311), CCR (n = 147), prostate (n = 132), and lung cancers (n = 89). It was independently associated with ...

Potentially life-threatening cutaneous adverse drug reactions (cADRs) are associated with commonly prescribed oral antibiotics, according to a large, population-based, nested case-control study of ...

A case-control study revealed that combinations of drugs for cardiovascular diseases and hypertension were frequently prescribed before a diagnosis of bullous pemphigoid (BP), but the risk associated ...

Objective The objective is to determine the association and absolute risk of femoroacetabular impingement syndrome (FAIS) for the development of radiographic hip osteoarthritis (RHOA). Methods This is ...

In a 17-year German cohort study, researchers uncovered that age, APOE ε4 status, and especially female sex play major roles in determining levels of Alzheimer’s-related blood biomarkers, offering new ...

Per- and polyfluoroalkyl substances (PFAS) exposure is linked to a 31% increased risk of type 2 diabetes (T2D), with perfluorooctane sulfonate being a significant contributor. Metabolomic profiling ...