There is a pressing need for new clinical tests that will help physicians distinguish drug-induced liver injury (DILI) from other, more common causes of liver injury, and that can identify which ...

Science Progress (1933-), Vol. 104, No. 1 (2021), pp. 1-16 (17 pages) Drug-induced liver injury (DILI) is one of the common adverse drug reactions and the leading cause of drug development attritions, ...

The integrated analysis of serum and fecal metabolites uncovers the significant disruption of bile acid metabolites as a key contributing factor in the pathogenesis of DILI. Our study offers promising ...

Biomarkers are traits that doctors measure in your blood, body fluids, and tissues. Experts also call them molecular markers and signature molecules. They can be signs of conditions, diseases, normal ...

Abstract and Introduction Current Status of DILI Biomarkers Promising Avenues for Discovery of New DILI Biomarkers Next Steps References The lymphocyte transformation test is commercially available in ...