Science Progress (1933-), Vol. 104, No. 1 (2021), pp. 1-16 (17 pages) Drug-induced liver injury (DILI) is one of the common adverse drug reactions and the leading cause of drug development attritions, ...

The integrated analysis of serum and fecal metabolites uncovers the significant disruption of bile acid metabolites as a key contributing factor in the pathogenesis of DILI. Our study offers promising ...

From simple physiological measurements and small molecules to imaging and histologic information, biomarkers found within the human body reveal valuable insights into health and disease. These key ...