Tropane alkaloids (TAs) are heterocyclic nitrogenous metabolites found across seven orders of angiosperms, including Malpighiales (Erythroxylaceae) and Solanales (Solanaceae). Despite the ...

Plant Physiology, Vol. 174, No. 1 (May 2017), pp. 47-55 (16 pages) Pyrrolizidine alkaloids (PAs) are toxic secondary metabolites that are found in several distantly related families of the angiosperms ...

Camptothecin is a monoterpene indole alkaloid (MIA) used to produce semisynthetic antitumor drugs. We investigated camptothecin synthesis in Camptotheca acuminata by combining transcriptome and ...

Researchers report the first successful microbial biosynthesis of the tropane alkaloids hyoscyamine and scopolamine, a class of neuromuscular blockers naturally found in plants in the nightshade ...

The elucidation of the biosynthetic pathway of ipecacuanha alkaloids shows how two distantly related plant species could develop the same substance independently Plants produce an enormous abundance ...

Complex polycylic structures are found in nearly every biosynthetic class of natural products. In particular, an amazing range of rigid densely functionalized polycylic compounds are formed from ...

With help from plant and human enzymes, yeast (Saccharomyces cerevisiae) can now make certain pharmaceutically important alkaloids naturally produced by plants. Previous efforts to biosynthesize ...

A recent study has unlocked the genetic secrets of Houttuynia cordata, an Asian herb renowned for its distinctive aroma and medicinal properties. This pioneering research unveils the plant’s genetic ...

Dramatically expands IP portfolio of cannabinoid synthesis related genes and enzymes Tackles known enzymatic and modification bottlenecks and challenges in biosynthesis Unlike Cannabis Sativa, which ...

Plants produce an enormous abundance of natural products. Many natural plant products are ancestry-specific and occur only in certain plant families, sometimes only in a single species. Interestingly, ...