In the gut, 5-HTT is located in epithelial cells, and its function is to inactivate locally ... although only three are expressed in bone 4. These findings suggest that Lrp5-related bone diseases ...

Researchers have identified Type R capillaries’ importance in bone remodelling in mature and ageing bones. This shows that ...

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

Many of these genes regulate the bone matrix, but a large number of the genes have never been studied in bone before ...

Bone-marrow-derived multipotent progenitor ... which is enhanced by interferon-γ released by activated T cells. MSCs also impair B-cell functions, such as antibody production.

Osteoporosis is typically treated with orally administered drugs, which may take up to a year to have a noticeable effect. A ...

Until now, it has not been understood how these cells function in the low-oxygen microenvironment of bone. Researchers at the Max Planck Institute for Molecular Biomedicine have achieved a ...

Penn researchers have developed a platform that emulates human bone marrow’s native environment. This breakthrough addresses ...

Bone marrow plays a crucial role in maintaining hematopoietic stem cells and bone homeostasis. However, research has been hindered by a lack of effective markers and monoclonal antibodies to ...

In a recent study, scientists have introduced an innovative imaging technique that provides an unparalleled view of the bone marrow’s intricate structure, focusing on leptin receptor-expressing (LepR+ ...