Scientists have mapped the sensory neurons in bone for the first time, and identified their dual role in reporting and ...

Osteocytes, the most abundant cells in bone tissue, have long been underestimated in their functional capacity. Traditionally viewed as passive entities, recent research has illuminated their pivotal ...

In a study published in Cell Research, researchers have identified a fibrous-layer resident subpopulation of P-SSCs labeled ...

Scientists uncovered how the protein Piezo1 translates physical activity into stronger bones, offering a path to exercise-mimicking therapies. Scientists from the Department of Medicine, School of ...

Scientists have identified a protein that blocks the activity of bone-forming cells (osteoblasts) by stopping them from maturing during the journey to sites of bone formation, a new study has found.

A new small molecule could treat and prevent excess bone formation. Fibrodysplasia ossificans progressiva (FOP) is an extremely rare disease estimated to affect about one in 2 million people worldwide ...

Hormonal changes after 30 can quietly weaken bone strength in women and increase the risk of osteoporosis later in life. An ...

Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from the Institute of Science Tokyo, Japan. Hypoxic conditions ...

Wif1 overexpression accelerated osteogenic differentiation by activating genes related to late-stage osteogenic differentiation and mitophagy processes. Moreover administering Wif1-overexpressing ...

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from ...