For decades, treating major depression has involved a frustrating cycle of trial and error, with patients cycling through medications and therapies while clinicians rely on symptoms and intuition more ...

Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting ...

Depression is a mental health disorder characterized by a recurrent or persistent sadness and a loss of interest in activities that were previously deemed pleasurable, sometimes accompanied by changes ...

Scientists identified two types of brain cells, neurons and microglia, that are altered in people with depression. Through genomic mapping of post-mortem brain tissue, they found major differences in ...

A genetic breakthrough reveals why mental health conditions often occur together. New research identifies five disorder groups sharing DNA patterns.

New research in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging shows that the brain of individuals who have recovered from depression retains a heightened sensitivity to negative cues, ...

Immune cells released from bone marrow in the skull in response to chronic stress and adversity could play a key role in symptoms of depression and anxiety, say researchers. The discovery—found in a ...

Assessing the brain at the Barbican, London, UK. Image by Tim Sandle. Assessing the brain at the Barbican, London, UK. Image by Tim Sandle. The medical benefits of mild electrical stimulation of the ...

Brain implants that deliver electric pulses can ease depression in people who aren't responding to psychiatric drugs, a new study says. Half of a small group of people who received brain implants ...