In mammalian cells, DNA double-strand breaks (DSBs) are repaired predominantly by the non-homologous end joining (NHEJ) pathway, which includes subpathways that can repair different DNA-end ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

DNA damage has been associated with aging and disease. Double-strand breaks are one of the worst forms of damage. New research shines a light on the repair process.

The findings, presented by Dr. Enrique Gonzalez-Duran and Prof. Dr. Ralph Bock from the Max Planck Institute of Molecular Plant Physiology in Nature Plants ("Suppression of plastid-to-nucleus gene ...

High-resolution cryo-electron microscopy has revealed the structural mechanism by which human RAD51 mediates strand exchange during homologous recombination, a key DNA repair pathway.

More often, the strand of DNA is permanently broken, which could potentially lead to additional genetic abnormalities in the embryo." Dr Nada Kubikova, University of Oxford.