These astonishing results indicate that DNA that was completely broken down can revert back ... et al. Double-strand breaks associated with repetitive DNA can reshape the genome.

The NTase domain binds to the broken DNA strands at and flanking the nick, the OB domain contacts the continuous template strand surrounding the nick, and the HhH domain binds both strands across the ...

The platform enables direct, unbiased genome-wide identification and quantification of the exact position of double strand DNA breaks in edited cells.

One important player is the "molecular matchmaker" RAD51, which attaches itself to broken DNA strands and helps them find their way to their sibling strand, which then serves as a template to ...

Specifically, they found that RNA molecules and the broken section of DNA can match up like puzzle ... RNA-mediated double-strand break repair by end-joining mechanisms, Nature Communications ...

When imposing repair on broken DNA strands during mitosis, some telomeres are seen to fuse together (one dot). Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...

These tails are substrates for strand-exchange proteins that catalyze invasion of homologous duplexes ... The enzyme is a target of potent anti-cancer drugs such as etoposide, which trap the protein ...