Partnership leverages AI-powered genome design to optimize AAV constructs, accelerate lead candidate selection, and improve drug substance manufacturability for rare and ultra-rare neuromuscular ...

We then determined the crystal structure of a MBP-Norrin/Fz4-CRD complex at 3.8 Å resolution, using the molecular replacement method with the Fz4-CRD, MBP, and Norrin structures as search models ...