CRISPR-Cas系统是细菌抵御病毒入侵的关键适应性免疫机制，而噬菌体等可移动遗传元件则进化出多种“反CRISPR”蛋白来对抗这一防御。研究发现，噬菌体可利用一类特殊的RNA分子来干扰CRISPR-Cas系统（RacrIF1）。然而，RacrIF1 ...

但讽刺的是，专利战打得火热，商业化却已悄然加速。全球首款CRISPR疗法Casgevy已获批上市，销售额稳步攀升，多家公司在研管线进入晚期临床。专利归属虽悬而未决，但投资人早已用脚投票：CRISPR相关美股公司市值回暖，Cathie Wood（木头姐 ...

以色列科学家借助CRISPR基因编辑技术，培育出苦味更淡的葡萄柚。这项研究有望提升葡萄柚的食用接受度，同时还可增强其抗病能力。相关成果发表于新一期《植物杂志》。 柑橘类水果的“酸”主要来自果酸含量，比如柠檬就格外酸涩；而“苦”则源于另一类化合物。研究表明，葡萄柚的苦味主要由一种叫柚皮苷的物质引起，与其结构相似的新橙皮苷和枸橘苷也起着重要作用。

Banas is associate director of research at the Gene Editing Institute at ChristianaCare, where Kmiec is founder and executive director. The medical promise of CRISPR gene editing can be seen most ...

CRISPR has the power to correct genetic mutations, but current delivery methods are either unsafe or inefficient, keeping the technology from reaching its full medical potential. With the power to ...

CRISPR will get easier and easier to administer. What does that mean for the future of our species? In 2016, I attended a large meeting of journalists in Washington, DC. The keynote speaker was ...

Megan Molteni reports on discoveries from the frontiers of genomic medicine, neuroscience, and reproductive tech. She joined STAT in 2021 after covering health and science at WIRED. You can reach ...

Humans have been selectively breeding cats and dogs for thousands of years to make more desirable pets. A new startup called the Los Angeles Project aims to speed up that process with genetic ...

CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...