Bagged in three layers of meninges and selectively fenced off by the blood brain barrier, our central nervous system (CNS) interacts within strict limits with our immune system. Protective ...

Steady-state memory-phenotype conventional CD4 + T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis Figure 3: T cells require Bhlhe40 for normal cytokine ...

New York, NY – The protein GM-CSF plays a critical role in maintaining immune tolerance in the gut, with defects in the protein increasing the susceptibility to inflammatory bowel diseases (IBD), ...