CHICAGO--(BUSINESS WIRE)--Celsis In Vitro Technologies Inc. (Celsis IVT), a division of the global life sciences company Celsis International plc, today announced the availability of Celsis InVitroCYP ...

The cytochromes P450 (CYPs) are the main enzyme family for metabolism of therapeutic drugs. CYP3A4 is the most active drug metabolizing CYP, and it plays a prominent role in adverse drug-drug ...

Light blue indicates the substrate-binding cavity inside the CYP enzyme. The CYP enzyme is unable to form a stable interaction with the atropisomer (aS)-CB45 because (aS)-CB45 collides (indicated by ...

Chemists in Germany have discovered a way to persuade a cytochrome P450 (CYP), an enzyme that normally oxidizes large molecules such as fatty acids, steroids, and terpenoids, to do its work on the ...

Sept. 16, 2003 — St. John's wort increases metabolism via the cytochrome P450 (CYP) enzyme system 3A4, according to the results of a study published in the Sept. 17 issue of The Journal of the ...

Personalized Medicine. 2010;7(4):421-426. In conclusion, plasma drug-level quantification and CYP enzyme profiling together offer some benefits in individualizing psychopharmacology, but the lack of ...