HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer. While indispensable for embryonic patterning ...

Fusion genes, arising from abnormal chromosomal rearrangements, are gaining recognition as pivotal players in cancer development. These genetic alterations result in the creation of hybrid genes with ...

In recent years, cancer immunotherapy has transformed the treatment landscape for a wide range of malignancies, offering ...

The intricate relationship between diet, metabolic disorders, and cancer progression has garnered significant attention in ...

A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by ...

For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German ...