CAR-T(嵌合抗原受体T细胞)疗法在血液系统恶性肿瘤的治疗中取得了突破性进展。然而,由于实体瘤的肿瘤微环境(TME)高度免疫抑制、肿瘤抗原表达的异质性及T细胞渗透能力受限,CAR-T在实体瘤治疗中面临显著挑战。 为克服这些问题,2月7日Nature Medicine的研究 ...
该研究首次在人类患者中验证了CAR-M疗法的安全性及可行性,并证明CT-0508能够靶向HER2阳性肿瘤,同时重塑肿瘤微环境以增强抗肿瘤免疫应答。 CAR-T(嵌合抗原受体T细胞)疗法在血液系统恶性肿瘤的治疗中取得了突破性进展。然而,由于实体瘤的肿瘤微环境(TME ...
Lou is a freelance journalist and content writer with a focus on the automotive world. After graduating from Coventry University (Automotive Journalism MA) in 2020, she worked in automotive e-commerce ...
For millions, purchasing a vehicle is one of the most significant transactions most people will ever make. Not only must new ...
该研究开发了一种mRNA-LNP递送系统,用于体内靶向定制CAR-M的腹腔编程,并进一步加深了对CAR-M疗法治疗实体瘤的调控和反馈机制的理解. 近日,中国科学院杭州医学研究所谭蔚泓院士、谢斯滔研究员和刘湘圣研究员等在预印本平台 bioRxiv上发表了题为:Intraperitoneal ...
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A new trademark filing revealed the name of the first BMW high-performance M electric car. The BMW M3 is going electric, likely under the name iM3. The rumors can finally be put to rest: BMW’s M3 is ...