A total of 115 patients with hypertension and LV hypertrophy (by echocardiography) were included. 13 Exclusion criteria were known secondary hypertension, renal failure, LV dysfunction (here defined ...

Oral erythromycin prolongs cardiac repolarization and is associated with case reports of torsades de pointes. Because erythromycin is extensively metabolized by cytochrome P-450 3A (CYP3A) isozymes, ...

Prolongation of the electrocardiographic QT interval, a measure of cardiac repolarization, is associated with arrhythmogenic disorders and is a risk factor for sudden cardiac death. Two genome-wide ...