Advances in cell line engineering and microfluidic technologies offer substantial opportunities to shorten timelines in cell line development (CLD). However, as with any innovation, optimizing these ...

Host Cell Line Selection: The first critical step is selecting the appropriate host cell line. This decision is based on factors such as growth characteristics, genetic stability, and productivity, ...

U.S. government researchers have made a significant step forward in developing a fully automated process for cell-line development. The National Institute of Allergy and Infectious Diseases (NIAID), ...

Luciferase-based reporter cell lines are invaluable for detecting cellular responses to signaling pathways in vitro, enabling high-throughput screening and profiling of inhibitors or activators. In ...

Cell line engineering and development play a critical role in the production of gene therapies by creating the potential for a stable and reproducible process, which can significantly reduce the cost ...

MONT-SAINT-GUIBERT, Belgium--(BUSINESS WIRE)--Cellistic, a cell therapy platform provider that partners with therapeutic developers to ensure cell therapies can achieve their full potential, has ...

This partnership provides the industry with cutting-edge options for mammalian-expressed products. OKLAHOMA CITY & MONTHEY, Switzerland--(BUSINESS WIRE)--ExcellGene SA, a leading Swiss biotech service ...

Cell line development continues to face technical and operational hurdles in transfection, clone selection, and media optimization. Manual screening, extended culture timelines, and fragmented data ...

Single cell isolation is a necessary step for a variety of applications from developing productive, stable cell lines for biologics manufacturing to developing CRISPR edited iPSCs for disease modeling ...