An international team of researchers led by Max Delbrück Center Scientific Director Professor Maike Sander, MD, has for the first time developed an organoid model of human pluripotent stem ...

Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination With Cyclin-Dependent Kinase 4/6 Inhibitors A total of 14,177 patients were ...

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair ...

Long-Term Survival and Biomarker Analysis Evaluating Neoadjuvant Plus Adjuvant Relatlimab (anti-LAG3) and Nivolumab (anti-PD1) in Patients With Resectable Melanoma Our study included a broad cohort of ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

Identifying and delineating cell structures in microscopy images is crucial for understanding the complex processes of life. This task is called "segmentation" and it enables a range of applications, ...

Mor than 800 million people worldwide are living with diabetes, according to World Health Organization (WHO) estimates, with numbers steadily increasing. Diabetic patients experience abnormally high ...

The integration of single-cell and spatial transcriptomics with advanced metabolic profiling tools has revolutionized the ...

Despite innovative new research, many cell and gene therapies do not make it all the way to the patients. Researchers and ...

Studying gene expression in a cancer patient's cells can help clinical biologists understand the cancer's origin and predict the success of different treatments. But cells are complex and contain many ...