Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4). Biologics targeting ...

Partnership unites AI and single cell technology to map immune dysfunction and improve drug discovery and development ...

UCLA scientists have developed advanced miniature 3D tumor organoid models that make it possible to study glioblastoma tumors ...

In an interview with Targeted Oncology, George Mulligan, PhD, discussed the key takeaways from analysis of the Immune Atlas ...

A study has traced immune activity at high resolution in the first living recipient of a gene-edited pig kidney and has reported that – even after clinicians suppressed T-cell rejection – ...

This illustration outlines the key role that gut-produced inosine plays in supporting immune cell development in the lung. When antibiotics disrupt the gut microbiota (dysbiosis), the amount of CD8+ ...

The influenza virus manipulates the body's gene regulation system to accelerate its own spread. A new study also shows that an already approved drug could help strengthen immune defenses -- though its ...

Orthopedic infections are common complications following surgery or trauma to bones, joints, muscles, ligaments, tendons, and ...

A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding ...

Andrew Monteith receives funding from the National Institute of Health. Research from my colleagues and I revealed that mitochondria play another key role in your immune response: sensing bacterial ...