The central dogma of molecular biology describes the flow of genetic information. It was first described by Francis Crick in 1956 as one-way traffic: as: "DNA makes RNA and RNA makes protein." A ...

The central dogma of molecular biology is key to understanding the relationship between genotype and phenotype, although it remains a challenging concept to teach and learn. We describe an activity ...

As cellular machines and processes that regulate the flow of genomic information have come into sharper focus, a new level of chemical control has become possible. The scope of such chemical ...

It’s among the most well-known rules in modern biology: Genetic information flows in one direction, from DNA to RNA to protein. But a recent discovery complicates and adds nuance to this so-called ...

For decades, RNA was seen as a simple slave to DNA. Newer research shows it has an active and critical role in every disease from Alzheimer's to cancer. One of the great revolutions in modern science ...

Small molecules have critical roles at all levels of biological complexity and yet remain orphans of the central dogma. Chemical biologists, working with small molecules, expand our understanding of ...

The core premise (central dogma?) of precision medicine – including both the White House’s initiative, as well as a range of other efforts – is that the integration of genetic information, EMR data, ...