Cholesterol plays an indispensable role in embryonic development, cell membrane integrity and the biosynthesis of steroid hormones. Disorders of cholesterol biosynthesis disrupt these vital processes, ...

Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

An editorial published in Brain Medicine raises the alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription ...

Salk researchers discover novel targets for bladder cancer therapeutics and demonstrate that a new combination of existing drugs, including statins, blocks tumor growth in mice LA JOLLA (January 14, ...