As a result of X chromosome inactivation, females are mosaic for cell lineages in which either the paternal or the maternal X chromosome is active, and, if inactivation were random, each lineage ...

在哺乳动物雌性早期发育中，X 染色体失活（X chromosome inactivation）会随机沉默两条 X 染色体之一。研究人员开展 X 连锁竞争（X - linked competition）主题研究，发现 X 染色体序列差异会引发克隆间竞争，影响机体发育及 X 连锁序列变异，这对理解 X 连锁人类疾病意义重大。

Exciting new data indicate that X-chromosome inactivation (XCI) is very far from the ‘all-or-none’ phenomenon that we thought it was when it was first discovered. When XCI was first described ...

Researchers have discovered that the structural protein SMCHD1 is required to prevent genes from both X chromosomes being expressed in female mammals.

X-chromosome inactivation varies across different areas of brains. Here, fluorescent imaging data from a mouse reveal where the father’s X chromosome is most active (white) and least active ...

Their results showed that X chromosome (chrX) inactivation (XCI), the process by which one of the two X chromosomes in female (XX) cells is inactivated, can also occur in male cancers.

Though visual representations of X inactivation are well known—the pattern of a calico cat’s fur, for instance—understanding of how X chromosome inactivation affects disease and development is still ...

X chromosome inactivation. Infographic: How Some X-Chromosome Genes Escape Inactivation. Amber Dance | | 4 min read. About one-quarter of the hundreds of genes on the inactivated X chromosome in XX ...

Female mammals carry two X chromosomes, while male mammals carry an X and a Y chromosome. The X chromosome carries a thousand genes, so in females, one of the X chromosomes must be silenced to avoid ...

In the spotlight: X chromosome inactivation. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2015 / 08 / 150818112615.htm. Radboud University.

X-chromosome inactivation is achieved courtesy of a molecule called Xist. The gene for Xist is present on all X chromosomes, including the single one male cells have.

Protein May Play Role In Sex Chromosome Inactivation Date: December 7, 2001 Source: Howard Hughes Medical Institute Summary: The decision to inactivate one of the two X chromosomes, which occurs ...