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New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...
When cilia go bad: Cilia defects and ciliopathies. Nature Reviews Molecular Cell Biology 8 , 880–893 (2007) doi:10.1038/nrm2278. Hildebrandt, F. & Otto, E. Cilia and centrosomes: a unifying ...
Primary cilia are important sensory organelles that play a role in cell signaling and development. “Sometimes people think of [primary cilium] as an antenna because they are coated in receptors and ...
New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...
Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...
The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.
Revealing new biology. Cilia are notoriously difficult to study. In brain cells, a single cilium, only tens of microns long, extends from a cell's surface into a jumble of other cells.Using ...
There, scientists reported that nerve cell cilia in C. elegans worms could float little packets containing chemical messages into the space between cells. Those signals may have a role in the ...
Cilia are hair-like structures that extend from the surface of almost all cell types of the human body. In addition to being "motors" that enable cell propulsion and fluid movement, cilia act as ...
He described cilia as cellular compartments where important proteins are brought together, as if in a Zoom meeting, to make decisions that guide a cell's development.
J ing Hughes, an endocrinologist at Washington University in St. Louis, was working late in the lab recently, imaging cilia in mouse pancreatic beta cells.These cilia, which are tiny hairlike ...