Left-right asymmetry is known to be established during early embryogenesis by a small cluster of cells termed the left-right organizer. Within this organizer, motile cilia beat rapidly to create a ...

A team led by UT Southwestern Medical Center researchers has uncovered the atomic structure of a protein complex pivotal to the function of motile cilia, the hair-like structures extending from the ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, ...

Researchers have uncovered a synapse on neurons’ tiny hair-like structures, which may facilitate long-term changes to genomic information in the nucleus. A new study from the Howard Hughes Medical ...

Cygb is a heme-containing globin protein that is not involved with oxygen transport or storage, unlike its pentacoordinate relatives, myoglobin and hemoglobin. Nevertheless, Cygb contains a ...

A new study now reveals that cilia in the organizer function as sensors for mechanical force exerted by flow to shape the left-right body plan of the developing embryo. Although the human body is ...

Researchers demonstrated that declining Hedgehog signaling from Cilk1 loss produces stepwise changes in tooth formation ...