In many cells of the human body, hair-like protrusions known as cilia act as antennae, allowing cells to receive signals from their environment and other cells. As cells grow and divide, each cilium ...

Cilia are evolutionarily conserved, microtubule-based organelles that project from the surface of most eukaryotic cells and play a central role in sensing ...

Researchers demonstrated that declining Hedgehog signaling from Cilk1 loss produces stepwise changes in tooth formation ...

Cilia are micrometer-sized biological structures that occur frequently in nature. Their characteristic high-frequency, three-dimensional beating motions (5–40 Hz) play indispensable roles inside the ...

Primary cilia are sensory organelles present on the cell surface; however, their physical structure has not been defined due to technical reasons. A new PNAS study examined primary cilia in human ...

Cygb is a heme-containing globin protein that is not involved with oxygen transport or storage, unlike its pentacoordinate relatives, myoglobin and hemoglobin. Nevertheless, Cygb contains a ...

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, ...

Left-right asymmetry is known to be established during early embryogenesis by a small cluster of cells termed the left-right organizer. Within this organizer, motile cilia beat rapidly to create a ...

Researchers have uncovered a synapse on neurons’ tiny hair-like structures, which may facilitate long-term changes to genomic information in the nucleus. A new study from the Howard Hughes Medical ...

Many cells in our body have a single primary cilium, a micrometer-long, hair-like organelle protruding from the cell surface that transmits cellular signals. Cilia are important for regulating ...