Background Aortic stenosis (AS) frequently coexists with heart failure (HF), but its prevalence, prognostic impact and management across the full HF spectrum remain incompletely characterised. Methods ...

One of the world’s most extensive birth cohorts is now entering later adulthood. At the University of Oulu in Finland, the Northern Finland Birth Cohort 1966 (NFBC1966) is launching a major new follow ...

Objective To characterise the risk of subsequent primary non-keratinocyte skin cancers (NKSCs) among adult-onset cancer survivors. Design Data analysis of this population-based cohort study was ...

Objective To investigate the association between sprint running biomechanics and sprint-related hamstring strain injury (HSI) in elite male football players. Methods This prospective cohort study ...

Background Insomnia symptoms are prevalent in older adults and linked to cardiovascular disease (CVD), but the role of long-term symptom trajectories remains unclear. We investigated associations ...

Background IBD is characterised by recurrent flares, but evidence on whether modifiable dietary factors influence flare risk ...

Main outcome measures Cumulative time dependent intake of preservatives, including those in industrial food brands, assessed using repeated 24 hour dietary records and evaluated t ...

This article describes the trajectory of adherence patterns among users of sodium-glucose cotransporter 2 (SGLT2) inhibitors. The authors found that baseline factors were unable to predict the ...

Pilot study met key 3-month efficacy endpoint with strong statistical significance (p=0.014); Revita-treated patients lost an additional 2.5% total body weight after stopping GLP-1 drugs vs. 10% ...