Mizzou opens its 2025 schedule on Thursday at 6:30 p.m. by hosting Central Arkansas of the Football Championship Subdivision in a game airing on SEC Network.

Week 0 features Portland State vs Tarleton State in an FCS clash as the Big Sky meets the United Athletic Conference.

Among them is a matchup between Stanford in Hawaii, which will be the final game of the weekend before the page turns to Week 1 next week. This will mark the fifth all-time matchup between Stanford and Hawaii and the first since the Cardinal opened the 2023 campaign with a 37-24 win over the Rainbow Warriors.