Four astronauts are set to depart the International Space Station Wednesday amid a health concern. The unprecedented early departure will leave behind a skeleton crew.

In a heartwarming and historic moment for space exploration, an American astronaut and two Russian cosmonauts launched to the International Space Station (ISS) on Thanksgiving Day 2025. The crew’s ...

"We were looking forward to the arrival of Expedition 74 aboard Soyuz MS-28, and made a holiday cake for them," TASS correspondent aboard the ISS, Alexey Zubritsky, said ISS, November 28. /TASS/.

The three-person crew will spend about eight months aboard the orbital laboratory conducting scientific research. This mission comes as the ISS marks 25 years of continuous human presence in orbit.