本文发现刺激GPi腹侧与GPe交界处的“甜点”区域,以及与小脑皮层(小叶IX、Crus I、Crus II)、默认模式网络和边缘网络功能连接的区域,与肌张力障碍患者在接受GPi-DBS治疗后更早出现症状改善显著相关。研究结果支持了小脑-边缘系统-基底节网络模型在肌张力 ...
本系统综述与元分析评估了深部脑刺激(DBS)对帕金森病(PD)患者UPDRS-III评分的影响,涵盖STN和GPi刺激目标、药物状态及刺激方式。结果显示DBS显著改善震颤、僵硬、动作迟缓和小舞蹈症,但对步态和语言功能效果不一,提示需个体化参数优化和患者选择。
September 28, 2011 (San Diego, California) — Deep-brain stimulation (DBS) to the subthalamic nucleus or globus pallidus internus has different effects on gait and balance in patients with Parkinson's ...
In a major study, investigators have compared how individuals with Parkinson's disease respond to deep brain stimulation (DBS) at two different sites in the brain. Contrary to current belief, patients ...