For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

Elegen sets a new benchmark for clonal, cell-free synthetic DNA with ENFINIA, delivering unmatched length and accuracy from ...

In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Reporting in Nature, scientists have identified a novel process that protects the ends of chromosomes from incorrectly applied DNA repair. Although DNA repair is a crucial mechanism that can protect a ...

Scientists manufacture many biotherapeutic products in immortalized cell lines, most commonly HEK293. Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in the body.

Precision DNA editing gene therapy achieves deep remissions in aggressive leukemia previously considered incurable.