疱疹病毒是一种广泛存在的双链DNA病毒，具有终生潜伏期，可引起多种疾病。尽管靶向DNA聚合酶的抗病毒药物是有效的，但不断增加的耐药性强调了寻找替代药物的必要性。解旋酶-引物酶抑制剂（HPIs）是一种很有前途的抗病毒药物，但其作用机制尚不明确。此外，解 ...

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.

Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Danish researchers believe that everyone should monitor their blood folate levels. They argue that a deficiency in folic acid ...

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns ...

FARGO, N.D.--(BUSINESS WIRE)--Aldevron, a global leader in the production of DNA, RNA and protein, has launched its latest innovation, Alchemy™ cell-free DNA technology. This revolutionary technology ...