Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

CDT1 inhibits the helicase activity of the MCM complex, thereby suppressing nascent strand synthesis in DNA replication in cultured human cells. This action results in fork collapse and DNA damage, ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Objectives Understanding the molecular changes in the preclinical synovium is crucial for identifying factors that drive ...

A brain disorder associated with chronic repeated head blows, may also have a genetic component. A new study from Boston Children’s Hospital reveals DNA damage, similar to Alzheimer’s disease in the ...