DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

The genetic connections between DNA repair pathways and human cancer predisposition have fueled interest in the proteins that recognize and repair specific sites of DNA damage. The repair enzymes are ...

In addition, a number of genes that have been implicated in cancer, such as the RAD group, have also been determined to encode proteins critical for DNA damage repair. As previously mentioned ...

PARylation is integral to many key cellular functions, including signaling modulation and DNA repair. PARylation is reversible and ... PARG inhibition results in increases in sensitivity to DNA damage ...

Thus, a 30-year-old woman has egg cells that are just as old. The egg cell’s ability to repair damage in its DNA is crucial to ensure that it remains functional for a long time and does not die. To ...

"The DNA inside our cells is constantly experiencing damage, and DNA repair is happening all the time to fix that damage and keep our cells healthy. Now, however, it seems these repair processes ...

A study, which was published in the journal Occupational & Environmental Medicine, found that melatonin seems to help actually some people repair DNA damage while sleeping. As you may know ...

Researchers observed a borderline statistically significant 1.8-fold increase in urinary 8-OH-dG excretion during day sleep in association with the melatonin intervention. HealthDay News — For ...

While nuclear DAAO activation kick-started DNA damage repair proteins and caused DNA strand breaks, mitochondrial-bound DAAO did not cause either of these effects. Additionally, DAAO-produced hydrogen ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

These variants control several common biological pathways, including those governing whether and how well a cell can repair damage to its DNA, how it produces energy, and how it interacts with and ...

This new research reveals that one of its metabolites, sucralose-6-acetate, can break up DNA and damage cells, raising concerns about its long-term health effects. Sucralose, an artificial ...