The DNA double helix is composed of two DNA molecules whose sequences are complementary to each other. The stability of the duplex can be fine-tuned in the lab by controlling the amount and location ...

DNA-encoded chemical library technologies are increasingly being adopted in drug discovery for hit and lead generation. DNA-encoded chemistry enables the exploration of chemical spaces four to five ...

Some biochemistry laboratories fashion proteins into complex shapes, constructing the DNA nanotechnological equivalent of Baroque or Rococo architecture. Yamuna Krishnan, however, prefers structurally ...

Professors Sara Snogerup Linse, Goran K. Hansson and Claes Gustafsson, members of the Nobel Assembly, talk to the media at a news conference at the Royal Swedish Academy in Stockholm October 7, 2015.

Studies of DNA’s repair mechanisms have won Tomas Lindahl, Paul Modrich and Aziz Sancar the 2015 Nobel Prize in chemistry. DNA encodes the instructions for building and conducting life. But it’s a ...

The chemists aren't going to be happy about this one. Over the last decade, the Nobel Prize in Chemistry has often gone to biochemistry, which to chemists is only sort-of real science. And this year's ...

In a new study in Nature, the Al-Hashimi Lab at Duke University has discovered an important way that some DNA mutations happen. Or more accurately, they have provided evidence for something James ...

Their work details how cells repair damaged DNA and preserve genes. And now three scientists — Tomas Lindahl, Paul Modrich and Aziz Sancar — have won the 2015 Nobel Prize in Chemistry. Their work ...

Benjamin Burke does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Rachel Litman Flynn receives funding from the NIH-NCI and Karin Grunebaum Research Foundation. Our cells are up against a daily onslaught of damage to the DNA that encodes our genes. It takes constant ...

Damage to your DNA is unavoidable. Every day our cells are bombarded by gene-splitting UV radiation or chemical carcinogens. Regular water inside our bodies can cause DNA damage. DNA damage is as ...