Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Replication initiators in both bacteria and eukaryotes are AAA+ proteins that bind and remodel origin DNA sequences, preparing them for chromosome duplication. Two new reports show that the bacterial ...

For 60 years, the DNA double helix has provided an iconic image of how our genetic information is held and how it reproduces. Now scientists at the University of Cambridge in the UK – where Watson and ...

DNA origami, a fascinating technology that uses algorithms to design self-assembling 2- and 3D nanostructures using DNA helices, has added a new member to its growing catalog: multilayered ...

BERKELEY, CA – Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form ...

DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

The tiny motor could help spark research into future applications such as building molecular factories for useful chemicals or medical probes of molecules inside the bloodstream to detect diseases ...

DNA origami is a technique used for the nanoscale folding of DNA to develop two-dimensional (2D) and three-dimensional (3D) shapes at a nanoscale range. No bigger than a virus, each of these ...