Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, ...

Replication initiators in both bacteria and eukaryotes are AAA+ proteins that bind and remodel origin DNA sequences, preparing them for chromosome duplication. Two new reports show that the bacterial ...

Researchers in the US and Germany have developed a new way to transform DNA into complex shapes by making the molecules twist and bend. The technique could be crucial for making nanoscale device ...

DNA origami, a fascinating technology that uses algorithms to design self-assembling 2- and 3D nanostructures using DNA helices, has added a new member to its growing catalog: multilayered ...

BERKELEY, CA – Repairing breaks in the two strands of the DNA double helix is critical for avoiding cancer. In humans and other organisms, a molecular machine called the MRN complex is responsible for ...

When an SSB appears, polymerase epsilon approaches the nick before retracing its steps thanks to its exonuclease, allowing fork reversal to take place. The nick is repaired as an SSB, and replication ...

Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form ...

(Nanowerk News) A human cell harbors roughly 2 meters of DNA, encompassing the essential genetic information of an individual. If one were to unwind and stretch out all the DNA contained within a ...

DNA origami is a technique used for the nanoscale folding of DNA to develop two-dimensional (2D) and three-dimensional (3D) shapes at a nanoscale range. No bigger than a virus, each of these ...

DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

Homologous recombination is one mechanism for repairing double-stranded DNA breaks. It involves the exchange of nucleotide sequences to repair damaged bases on both strands of DNA through the ...