遗传性癌症综合征通常由影响 DNA 修复通路的致病性变异引起，其中同源定向修复（HDR）或错配修复（MMR）与妇科癌症最相关。HDR 以姐妹染色单体为 ...

Nucleic acid vaccines deliver the instructions to make specific virus proteins directly into human cells as either RNA or DNA. The advantages of such vaccines are that they are easy to make in ...

In the past decade, DNA vaccines have emerged as a potential favoured strategy for inducing immunity. Not only are they cost-effective and free of infection risk, but they can elicit both strong ...

2). DNA vaccines contain the nucleotides encoding an antigenic portion of the virus such as the viral core region or envelope region. The DNA is taken up into the host cell, translated ...

Genetic vaccines, sometimes called naked-DNA vaccines, are currently being developed to fight diseases such as AIDS. The goal of these vaccines is to use a gene from a pathogen to generate an ...

There are many potential problems and unanswered questions concerning the use of DNA vaccines. [14] The possibility of insertional mutagenesis is a concern that needs to be more rigorously tested.

Wang, Alex Kim, and Kevin Kim found that genetic DNA mutations contaminated some severe acute respiratory syndrome coronavirus 2 messenger RNA vaccines, called mRNA, which use messenger RNA ...