Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

A team of researchers have identified a fundamental mechanism that links the 24-hour circadian cycle to the precise repair of DNA breaks. This study, conducted by researchers from the Andalusian ...

Once failed in high school chemistry due to a teacher’s judgement, Tomas Lindahl later reshaped the same discipline. Awarded ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Scientists in Sweden and Norway have uncovered a promising way to spot Parkinson’s disease years—possibly decades—before its most damaging symptoms appear. By detecting subtle biological signals in ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or ...