Researchers have uncovered a source of "replication stress" during DNA replication, shedding light on a new cancer target.

As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

Conjugation is a form of horizontal gene transfer that allows the exchange of genetic material between two organisms or cells ...

A recent review highlights the critical role of DNA exonucleases and endonucleases in immune response and disease management, shedding new light on their potential applications in genomic stability, ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

Researchers have uncovered mechanisms by which mobile genetic elements integrate into the chromosomes of bacteria with linear genomes.

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

Nearly six years after DNA analysts claimed to identify the notorious London serial killer known as “Jack the Ripper,” a victim’s family is demanding a police investigation into the claims.

Early diagnosis of lung cancer is a critical priority in clinical practice. It may help reduce the rate of lung-cancer-related mortality, extend ...