Without a connecting link, the CMG complex could just "run off" and leave pol-a/primase behind. This would create long regions of vulnerable ssDNA. Therefore, the second rule in DNA replication is ...

DNA is a complex molecule that consists of two strands coiled around each other to form ... This process is essential for the proper functioning and survival of all living organisms. DNA replication ...

Accurate transmission of the genetic information requires complete duplication of the chromosomal DNA each cell division cycle. However, the idea that replication forks would form at origins of DNA ...

Announcing a new article publication for Zoonoses journal. Methicillin resistant Staphylococcus aureus (MRSA) and Vancomycin ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous ... These include the ATM and ...

"Living organisms have evolved complex pathways to sense, signal, and repair damaged DNA," he says ... in protecting against ...