During DNA replication, the unwinding of strands leaves ... effective approach is to find proteins that directly bind to both enzymes. However, that requires us to understand the molecular ...

During DNA replication, special enzymes move up along the DNA ladder, unzipping the molecule as it moves along. New nucleotides move in to each side of the unzipped ladder. The bases on these ...

Cells employ an arsenal of editing mechanisms to correct mistakes made during DNA replication. How do they work, and what happens when these systems fail?

The enzymes that handle DNA molecules are often called "polymerases," but the -ase suffix denotes an enzyme. When not ...

DNA replication is the process by which the DNA molecule makes an exact copy of itself during cell division. The double helix unwinds, and each strand serves as a template for the synthesis of a new ...

In DNA replication, the "leading" strand forges ... halt a "runaway" strand by slowing it down so the rest of the enzymes can catch up. Kowalczykowski said the study opens up a new way of thinking ...

During DNA replication, the complementary base pairing of thymine with adenine ensures the accurate copying of genetic information. DNA polymerase enzymes use the existing DNA strand as a template and ...

DNA replication is a tightly controlled process ... Much of this work falls to enzymes called polymerases, which assemble the building blocks of DNA. On their own, however, polymerases aren ...

DNA achieves this feat of storing, coding and transferring biological information though its unique structure. Replication of DNA DNA replication is the process by which a cell makes an identical ...

Actually, that's DNA's main purpose: to make proteins within the cell. These proteins, which include enzymes that do specialized jobs, control the activities of the cell. Different cells have ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant ...

My scientific interests center on nucleases, a functionally diverse class of enzymes that catalyze the cleavage of phosphodiester bonds to support a wide breadth of pathways, including DNA replication ...