LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged DNA.

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more ...

Their findings, which were published March 7 in Science, one of world’s leading scientific journals, not only reveal new details about how secondary DNA structures like G4s can impede DNA replication, ...

DNA replication occurs in the S phase of the cell cycle. DNA replication is the process where DNA copies itself. This happens so that old cells can make new cells.

Protein involved in balancing DNA replication and restarting found USP50 protein helps balance nuclease and helicase activity during critical processes ...

Humans and baker's yeast have more in common than meets the eye, including an important mechanism that helps ensure DNA is copied correctly, reports a pair of studies. The findings visualize for ...

In a study recently published in Science, a research team from the Institute of Microbiology of the Chinese Academy of Sciences revealed the working mechanism of Monkeypox virus (MPXV) DNA polymerase.

Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer.

The identification of USP50's role provides a new insight into the DNA replication process and could lead to a greater understanding of how some hereditary conditions develop.

Technology DNA nanobots can exponentially self-replicate. Tiny machines made from strands of DNA can build copies of themselves, leading to exponential replication.