DNA damage that causes replication forks to stall can be bypassed via translesion synthesis (TLS). New work has identified a bifunctional human primase and TLS polymerase, PrimPol, that ...

RNA primers for DNA replication are usually synthesized by specialized enzymes, the primases 1.However, some replication systems have evolved to use cellular DNA-dependent RNA polymerase for ...

By controlling protein synthesis within each cell, the genes that make up DNA control the life of the entire organism. ... DNA Replication. All Wound Up. Glossary. Back to first page of DNA Workshop: ...

It follows a previous report showing that the Werner syndrome protein WRN and its interacting protein WRNIP1 are indispensable for translesion DNA synthesis (TLS) by Y-family DNA polymerases (Pols).

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind ...

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published ...

Cell identity is preserved during DNA replication by a histone ... as well as the synthesis of complementary DNA for ... Mrc1 does this by binding histones alone and with another protein ...

DNA replication and repair are critical processes that ensure the correct genetic material of a biological system is carried on. DNA continually undergoes a process of replication and division and ...

Synthesis of 32 P-Labeled DNA Chain and Its Subsequent Enzymatic Degradation by Micrococcal DNase and Calf-Spleen Phosphodiesterase to 3′ Deoxyribonucleotides (Modified from Kornberg 37).

Their findings, which were published March 7 in Science, one of world’s leading scientific journals, not only reveal new details about how secondary DNA structures like G4s can impede DNA replication, ...

The Rqc2 protein (yellow) binds tRNAs (dark blue, teal), which add amino acids (bright spot in middle) to a partially-made protein (green). The complex binds the ribosome (white) / Janet Iwasa, Ph ...