DNA–protein cross-links (DPCs) represent a severe form of DNA damage that can disrupt essential chromatin-based processes.

Researchers at Duke University used CRISPR technologies to discover previously unannotated stretches of DNA in the ‘dark genome’ that are responsible for controlling how cells sense and respond to the ...

Inside human cells, biology has pulled off the ultimate packing job, figuring out how to fit six feet of DNA into a nucleus ...

New ultra-detailed imaging exposes the hidden structure and behavior of chromatin condensates — and hints at how their ...

Fluorogenic DNA aptamers produce light only in the correct structural state, enabling programmable molecular logic, biosensing, DNA origami integrity reporting, and reusable mRNA detection through ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

A research team at Florida State University's Institute of Molecular Biophysics and Department of Chemistry and Biochemistry ...