LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

Startling evidence from Sheffield University reveals how common lifestyle choices can seriously damage sperm quality, ...

Cigarette smoke causes cancer primarily by damaging the DNA. A new study that mapped these damages has revealed that the way ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, ...

Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals.

Sunburn has traditionally been attributed to UV-induced DNA damage, but it turns out that this is not the full truth.

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

If these DNA breaks aren't repaired, they can prompt cells to self-destruct, or failing that, become cancerous.As LIG4 syndrome impairs this response, people with the condition are particularly ...