Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor ...

A new hereditary condition has been discovered that affects patients’ ability to repair DNA – leaving them both at greater risk of developing blood cancer, and unable to repair some of the damage ...

A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet ...

A new paper published in Science Translational Medicine describes an experimental drug capable of repairing DNA damage caused by disease. Developed by scientists at Cedars-Sinai, the potential ...

RIVERSIDE, Calif. -- A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings ...